Fatal breakthrough Scedosporium apiospermum (Pseudallescheria boydii) brain abscess during therapy for invasive pulmonary aspergillosis in a patient following high-risk allogeneic BMT
نویسندگان
چکیده
منابع مشابه
A fatal pseudallescheria boydii brain abscess.
We present the clinical and radiological features of pseudallescheria boydii infection in a middle aged woman who presented with right frontal pseudallescheria abscess after two years use of prednisolone for rheumatoid arthritis. Despite early surgical excision and intravenous antifungal treatment she died after 7 weeks despite aggressive therapy.
متن کاملHuman phagocytic cell responses to Scedosporium apiospermum (Pseudallescheria boydii): variable susceptibility to oxidative injury.
Scedosporium apiospermum (Pseudallescheria boydii) is an emerging opportunistic filamentous fungus that causes serious infections in both immunocompetent and immunocompromised patients. To gain insight into the immunopathogenesis of infections due to S. apiospermum, the antifungal activities of human polymorphonuclear leukocytes (PMNs), mononuclear leukocytes (MNCs), and monocyte-derived macrop...
متن کاملSusceptibility of Pseudallescheria boydii and Scedosporium apiospermum to new antifungal agents.
Hyalohyphomycoses caused by Pseudallescheria boydii and Scedosporium apiospermum have recently been on the increase. To find the appropriate treatment for this emerging disease, we examined the antifungal susceptibility of 10 isolates of P. boydii and 17 isolates of S. apiospermum, most of which were isolated from clinical specimens. When the NCCLS M38-P microdilution method was used, itraconaz...
متن کاملRare case of multiple brain abscess – Scedosporium apiospermum
Introduction Scedosporium apiospermum is the asexual form of fungus Pseudallescheria boydii which is commonly found in soil and sewage. It usually causes cutaneous infection (mycetoma) and otitis externa and in rare circumstances causes invasive disease in immunocompromised patients, which can involve the central nervous system with devastating prognosis. We report a case of brain abscess cause...
متن کاملAssessing micafungin/triazole combinations for the treatment of invasive scedosporiosis due to Scedosporium apiospermum and Scedosporium boydii.
OBJECTIVES Scedosporium infections are associated with high therapeutic failure rates. Combination therapy may be an alternative approach to improve outcome. The in vitro and in vivo efficacy of micafungin plus posaconazole or plus voriconazole was investigated herein. METHODS Scedosporium boydii (n = 17) and Scedosporium apiospermum (n = 26) were tested using the chequerboard method accordin...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2002
ISSN: 1201-9712
DOI: 10.1016/s1201-9712(02)90315-2